Logo Leibniz Universität Hannover
Logo: HOT – Hanover Centre for Optical Technologies
Logo Leibniz Universität Hannover
Logo: HOT – Hanover Centre for Optical Technologies
  • Zielgruppen
  • Suche
 

Biophotonics | Life Sciences | Environmental Analytics

As part of its applied research in optical technologies, the HOT works on several focal topics from the fields of biophotonics, life sciences, and environmental analytics.

Currently, our work focuses on 

  • microplastics: online-detection in flowing drinking water
  • microalgae: carotenoid analysis and effects of environmental stress
  • bacteria: non-invasive analysis of relative relatedness („in vivo phylogeny“)
  • biofilms: non-invasive observation over time, species identification, and 3D structure
  • human skin: optical analytics (dermatoscopy, melanoma thickness, quantification of carotenoids, vitamin D synthesis)
  • inner ear: non-invasive optical diagnostics
  • proteins: functional analysis

 

For this, we are working on new or improved experimental and data analysis methods

  • multivariate and cluster analysis: for the discrimination and grouping of spectra
  • Raman Resonance Profiles: high-resolution resonance profiles, molecular identfication, and tunable Rayleigh-filters
  • simulation and image processing: Raman spectra, OCT, opto acoustics, photophysics and -chemistry

 

Our most often used optical methods are

  • confocal Raman microscopy (spatial resolution at cell level; molecular information)
  • resonance Raman spectroscopy (molecular and molecular group-information)
  • absorption- and transmission spectroscopy
  • holographic microscopy
  • opto acoustics
  • optical coherent tomography (OCT)

and the combination of these methods.

Related projects

Biophotonics and Analytics

OPTIMUS -Raman spectroscopy of microplastics, microbes, and trace elements

Bild zum Projekt OPTIMUS - Ramanspektroskopie an Mikroplastik, Mikroben und Spurenstoffen

Supervisor:

Prof. Dr. Bernhard Roth

Researcher:

Dr. Ann-Kathrin Kniggendorf

Duration:

1.3.2016 - 28.2.2019

Funded by:

Bundesministerium für Bildung und Forschung (BMBF)

Brief description:

online detection of contaminated microplastics in streaming drinking water with Raman spectroscopy for the BMBF joint project OPTIMUS.

 

| details |

 

Smartphone based optical point of care tests

Bild zum Projekt Smartphone-gestützte optische Schnelltests für diagnostische Anwendungen

Supervisor:

Dr. Kort Bremer, Prof. Bernhard Roth

Researcher:

Dr. Maik Rahlves, Dipl.-Kffr. Rima Rifai, Dr. Johanna Walter

Funded by:

Bundesministerium für Wirtschaft und Energie (BMWi) und Europäischer Sozialfond (ESF)

Brief description:

Developing of Smartphone based point of care tests using aptamer functionalized surface plasmon (SPR) sensors.

 

| details |

 

Melanomdickenbestimmung mittels Optoakustik und OCT

Bild zum Projekt Melanomdickenbestimmung mittels Optoakustik und OCT

Supervisor:

Prof. Dr. Bernhard Roth, Prof. Dr. Uwe Morgner, Dr. Maik Rahlves, Dr. Merve Wollweber

Duration:

09.2013 - 01.2017

Funded by:

BMBF

Brief description:

Entwicklung eines Verfahren zur präoperativen Bestimmung der Dicke von Melanom-verdächtigen Hautläsionen.

 

| details |

 

Hautkrebsscreening (HKS)

 

Supervisor:

Dr. Merve Wollweber

Researcher:

Dr. Chandrajit Basu

Brief description:

Research on a digital system for dermatoscopy with enhanced diagnostic capabilities for automated whole-body-cancer-screening.

 

 

RRS-OA

Bild zum Projekt RRS-OA

Supervisor:

Dr. Merve Wollweber

Researcher:

Dr. Merve Wollweber

Funded by:

DFG

 

| details |

 

OCT

Bild zum Projekt OCT

Supervisor:

Dr.-Ing. Maik Rahlves, Prof. Dr. Bernhard Roth

Researcher:

Dr.-Ing. Maik Rahlves

 

| details |

 

ODONTO

Bild zum Projekt ODONTO

Supervisor:

alexander.leishot.uni-hannover.de

Researcher:

Dr. Alexander Leis

 

| details |

 

Research Initiative "Water and Security"

Bild zum Projekt Forschungsinitiative "Wasser und Sicherheit"

Supervisor:

Dr. Merve Wollweber, Prof. Dr. Bernhard Roth

Researcher:

Dr. Ann-Kathrin Kniggendorf

 

| details |