Generative AI for enhanced skin cancer diagnosis, dermatologist training, and patient education

Verfasst von

Lennart Jütte, Sandra González-Villà, Josep Quintana, Martin Steven, Rafael Garcia, Bernhard Roth

Abstract

The early detection and monitoring of suspicious skin lesions are essential for effective dermatological diagnosis and treatment, particularly in understanding the progression of nevi to melanoma. To advance this understanding, we developed a simulation framework that models the transformation of nevi into melanoma using Cycle-Consistent Generative Adversarial Networks and frame interpolation to generate a detailed dataset of simulated lesion progressions. Optical flow analysis was applied to these dermoscopic image sequences, providing quantitative insights into lesion transformations and dynamic changes. Heatmap visualizations and optical flow vectors highlighted regions of significant activity and confirmed the fidelity of the simulated transformations. Additionally, we demonstrate how this new approach can visually complement existing textual explainable AI methods in dermatology, enhancing interpretability and trust in diagnostic outcomes. These findings represent a significant step toward improving dermatological diagnostics, patient education, and the early detection of melanoma.

Details

Organisationseinheit(en)
Hannoversches Zentrum für Optische Technologien (HOT)
PhoenixD: Simulation, Fabrikation und Anwendung optischer Systeme
Externe Organisation(en)
Coronis Computing S.L.
University of Girona
Typ
Aufsatz in Konferenzband
Publikationsdatum
19.03.2025
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Elektronische, optische und magnetische Materialien, Atom- und Molekularphysik sowie Optik, Biomaterialien, Radiologie, Nuklearmedizin und Bildgebung
Ziele für nachhaltige Entwicklung
SDG 3 - Gute Gesundheit und Wohlergehen
Elektronische Version(en)
https://doi.org/10.1117/12.3042664 (Zugang: Geschlossen )

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