Biophotonics & Analytics: Confocal Raman Microscopy

Confocal Raman microscopy combines the properties of confocal microscopy - high, spatial resolution in 3D - with the advantages of Raman spectroscopy - precise substance identification via the vibrational modes of the involved molecules.

The HOT uses confocal Raman microscopy for example to

• non-invasively analyze living biofilms
• non-invasively identify bacteria species
• detection of microplastics in complex environmental samples
• functional analysis of proteins, peptides, and amino acids

often using specific molecular resonances for signal enhancing or directly in the form of resonance Raman spectroscopy.

See also

• Thomas Dieing, Olaf Hollricher, Jan Toporski (Eds), Confocal Raman Microscopy, Springer 2010,
  ISBN 978-3-642-12521-8, e-ISBN 978-3-642-12522-5
• Arnaud Zoubir (Edt.), Raman Imaging, Springer 2012,
  ISBN 978-3-642-28251-5, e-ISBN 978-3-642-28252-2
• Pavel Matousek, Michael D. Morris (Eds.), Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields, Springer 2010,
  ISBN 978-3-642-02648-5, e-ISBN 978-3-642-02649-2

Downloads

• Poster as PDF for Download
  Confocal Resonance Raman Spectroscopy: analyzing aquaeous multispecies biofilms in vivo